SCHEMBL1949112

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1948938	0.85	NOS3 (0.50)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL12549325	0.79	NOS3 (0.43)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL8345724	0.78	NOS3 (0.59)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL2831934	0.77	NOS2 (0.48)	NOS3NOS2IDH1ALDH1A1SMN1; SMN2
	SCHEMBL15705802	0.75	KMT2A (0.53)	MAPK1SMN1; SMN2NPC1RAB9AKDM4E
	SCHEMBL12963699	0.74	NOS3 (0.55)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL23482212	0.73	GAA (0.56)	NOS3NOS2MAPK1LCKALDH1A1
	SCHEMBL12933368	0.73	NOS3 (0.53)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL7797450	0.73	NOS3 (0.53)	NOS3NOS2IDH1MAPK1LCK
	SCHEMBL11454904	0.73	NOS3 (0.53)	NOS3NOS2IDH1MAPK1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.