Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194934 | 0.82 | HDAC3 (0.46) | TGFBR1ALDH1A1KDM4E | |
| SCHEMBL12967924 | 0.81 | — | — | |
| SCHEMBL8984421 | 0.81 | TGFBR1 (0.42) | TGFBR1ALDH1A1TDP1KDM4E | |
| SCHEMBL19579925 | 0.78 | TDP1 (0.39) | TGFBR1ALDH1A1TDP1 | |
| SCHEMBL195107 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL2926477 | 0.77 | HSP90AA1 (0.50) | ALDH1A1KDM4E | |
| SCHEMBL4157016 | 0.77 | TERT (0.35) | TGFBR1KDM4E | |
| SCHEMBL194027 | 0.76 | TGFBR1 (0.38) | TGFBR1ALDH1A1TDP1KDM4E | |
| SCHEMBL5681532 | 0.76 | TGFBR1 (0.38) | TGFBR1ALDH1A1TDP1KDM4E | |
| SCHEMBL12967384 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213334-A1 | Mixture of cationic polymer, anionic polymer and drug, that forms blended coatings and/or hydrogel coatings for controlled release of said drug from medical devices coated with or containing such media | Surmodics Coatings, LLC | 2008-09-04 | — | — | US | disclosed |
| WO-2008042748-A2 | POLYELECTROLYTE MEDIA FOR BIOACTIVE AGENT DELIVERY | SURMODICS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |