SCHEMBL195065

SCHEMBL195065

C=COc1cccc(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
RHEB Q15382 1/20 0.40
TSHR P16473 3/20 0.38
CYP1A2 P05177 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
TP53 P04637 1/20 0.38
CYP2C19 P33261 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PNMT P11086 2/20 0.35
IDO1 P14902 2/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CYP2A6 P11509 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194684 0.82 ALDH1A1 (0.44) ALDH1A1TSHRTDP1SMN1; SMN2SLC6A2
SCHEMBL29960351 0.82 ALDH1A1 (0.44) ALDH1A1TSHRTDP1SMN1; SMN2SLC6A2
SCHEMBL2095443 0.78 ALDH1A1 (0.43) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL1547749 0.78 ALDH1A1 (0.40) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL315903 0.75 ALDH1A1 (0.43) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL6325195 0.74 RHEB (0.60) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL11766505 0.74 PNMT (0.48) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL11179875 0.74 HTR2C (0.47) ALDH1A1TSHRCYP1A2TDP1CYP3A4
SCHEMBL10370306 0.74 ALDH1A1 (0.40) ALDH1A1RHEBTSHRCYP1A2TDP1
SCHEMBL29592755 0.73 ADRA2B (0.43) ALDH1A1TSHRTDP1TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
WO-2025011754-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2025-01-16 WO disclosed
EP-4114825-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2024-11-20 EP disclosed
CN-113316744-B Oxime ester photoinitiators with special aroyl chromophores 巴斯夫欧洲公司 2024-07-30 CN disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
EP-1778636-A1 OXIME ESTER PHOTOINITIATORS Ciba SC Holding AG (CH) 2007-05-02 EP disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 WO disclosed
WO-2006024617-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024619-A1 COMPOSITIONS CONTAINING PHTHALOCYANINE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024618-A1 CYANOPYRIDINE-BASED AZO DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
CN-1720245-A Oxime ester photoinitiators with heteroaryl groups CIBA SC HOLDING AG (CH) 2006-01-11 CN disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885RHEB 4097/4885TSHR 528/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885RHEB 4097/4885TSHR 528/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 964/4885RHEB 3164/4885TSHR 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.