Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670220 | 0.83 | FSHR (0.50) | MEN1KMT2ALMNAHPGDFSHR | |
| SCHEMBL1948554 | 0.78 | FSHR (0.48) | MEN1KMT2ALMNAHPGDHTT | |
| SCHEMBL8585756 | 0.73 | KMT2A (0.56) | MEN1KMT2ARAB9AMGLLGLA | |
| SCHEMBL1949617 | 0.72 | CTSL (0.44) | FSHR | |
| SCHEMBL4769268 | 0.71 | HPGD (0.73) | MEN1KMT2ARAB9ALMNAHPGD | |
| SCHEMBL16682333 | 0.70 | LMNA (0.50) | RAB9ALMNA | |
| SCHEMBL27919371 | 0.70 | DGKA (0.50) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL5598339 | 0.69 | CHRNB2 (0.47) | MEN1KMT2ARAB9AMGLLHPGD | |
| SCHEMBL27411822 | 0.69 | PLAAT3 (0.52) | KMT2ALMNAHPGD | |
| SCHEMBL5112506 | 0.67 | TDP1 (0.48) | MEN1KMT2ARAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2011-06-09 | — | — | US | disclosed |
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | HCAR2, PAH, PTGES2 | MEN1 4724/4885KMT2A 2304/4885RAB9A 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.