Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15787453 | 0.80 | SLC6A2 (0.43) | HDAC3HDAC1HDAC2HDAC8MMP13 | |
| SCHEMBL15787465 | 0.80 | SLC6A2 (0.43) | HDAC3HDAC1HDAC2HDAC8MMP13 | |
| SCHEMBL8326197 | 0.78 | DNM1 (0.55) | NPC1DNM1GAA | |
| Hydrochloric Acid SCHEMBL3666100 | 0.77 | ALDH1A1 (0.47) | NPC1DNM1GAA | |
| SCHEMBL20019954 | 0.77 | SLC6A2 (0.48) | MMP13SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13349408 | 0.74 | OPRK1 (0.40) | DNM1GAA | |
| SCHEMBL13333688 | 0.73 | BCHE (0.46) | DNM1 | |
| SCHEMBL8769305 | 0.72 | ADRB2 (0.43) | DNM1 | |
| SCHEMBL14532283 | 0.71 | DNM1 (0.55) | DNM1 | |
| SCHEMBL19122419 | 0.71 | DNM1 (0.55) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185261-A1 | MOSAPRIDE ACTIVE METABOLITES, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | 沈阳药科大学 | 2017-11-02 | — | — | WO | disclosed |