Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3666100 | 0.89 | ALDH1A1 (0.47) | DNM1NPC1LMNACYP2D6GAA | |
| SCHEMBL2915394 | 0.82 | DNM1 (0.55) | DNM1NPC1LMNAMEN1KMT2A | |
| SCHEMBL14532283 | 0.81 | DNM1 (0.55) | DNM1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL19122419 | 0.81 | DNM1 (0.55) | DNM1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL19545296 | 0.78 | HDAC3 (0.46) | DNM1NPC1GAA | |
| SCHEMBL16434845 | 0.75 | LOXL2 (0.50) | CYP2D6CYP2C19LOXL2 | |
| SCHEMBL13349408 | 0.75 | OPRK1 (0.40) | DNM1CYP2D6POLBPLA2G1BATG4B | |
| SCHEMBL13330952 | 0.74 | LMNA (0.60) | DNM1NPC1LMNAMEN1KMT2A | |
| SCHEMBL11371821 | 0.74 | GBA1 (0.41) | DNM1MEN1KMT2AGAALOXL2 | |
| SCHEMBL1796909 | 0.73 | LMNA (0.77) | LMNAMEN1KMT2ACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185261-A1 | MOSAPRIDE ACTIVE METABOLITES, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | 沈阳药科大学 | 2017-11-02 | — | — | WO | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |