Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385746 | 0.97 | ALDH1A1 (0.50) | ALDH1A1MAPK1RAB9ANPC1HSD17B10 | |
| SCHEMBL619546 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1RAB9ANPC1HSD17B10 | |
| SCHEMBL2960 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1RAB9ANPC1HSD17B10 | |
| SCHEMBL21382696 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1HSD17B10BCL2L1CYP1A2 | |
| SCHEMBL28980880 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1HSD17B10BCL2L1CYP1A2 | |
| SCHEMBL2450702 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1HSD17B10BCL2L1CYP1A2 | |
| SCHEMBL2448213 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1HSD17B10BCL2L1CYP1A2 | |
| SCHEMBL2448958 | 0.80 | MAOA (0.48) | ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL24983 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1HSD17B10BCL2L1CYP1A2 | |
| SCHEMBL4624349 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPK1RAB9ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | claimed |
| US-9278146-B2 | Peptide derivative and use of the same | KYOTO UNIVERSITY (JP) | 2016-03-08 | — | — | US | claimed |
| WO-2013045495-A1 | PYRANO[3,2-c][2]BENZOPYRAN-6(2H)-ONE DERIVATIVES AND USES THEREOF | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2013-04-04 | — | — | WO | claimed |
| EP-2573088-A1 | Pyrano[3,2-c]benzopyran-6(2h)-one derivatives and uses thereof | Prous Institute for Biomedical Research, S.A. (ES) | 2013-03-27 | — | — | EP | claimed |
| US-20110003757-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING FATTY LIVER DISEASE | ASTELLAS PHARMA INC. (JP) | 2011-01-06 | — | — | US | claimed |
| EP-2236137-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF FATTY LIVER DISEASES | Astellas Pharma Inc. (JP) | 2010-10-06 | — | — | EP | claimed |
| US-20090005390-A1 | NOVEL QUINUCLIDINE DERIVATIVES AND THEIR USE | NEUROSEARCH A/S | 2009-01-01 | — | — | US | claimed |
| US-20050245567-A1 | Novel quinuclidine derivatives and their use | NEUROSEARCH A/S (DK) | 2005-11-03 | — | — | US | claimed |
| EP-1532144-A1 | NOVEL QUINUCLIDINE DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2005-05-25 | — | — | EP | claimed |
| WO-2004016608-A1 | NOVEL QUINUCLIDINE DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2004-02-26 | — | — | WO | claimed |
| WO-2024139061-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE WITH UNPROTECTED AMINO ACID AS AMINE COMPONENT | 广州医科大学 | 2024-07-04 | — | — | WO | disclosed |
| CN-118256177-A | Composition for forming adhesive layer, laminate, method for producing adhesive layer, method for producing laminate, and method for treating laminate | 日铁化学材料株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-118255947-A | (Meth) acrylic acid copolymer and method for producing same | 日铁化学材料株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-118109145-A | Adhesive composition, adhesive layer, polarizing plate with adhesive layer, and display device | 住友化学株式会社 | 2024-05-31 | — | — | CN | disclosed |
| CN-110361942-B | Electrophotographic photoreceptor, process cartridge, image forming apparatus, and imide compound | 富士胶片商业创新有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-5846991-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5840909-A | Pyrazole derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5817828-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS; VISION DEFECTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5721264-A | EXHIBIT ANTAGONISTIC EFFECT AGAINST ANGIOTENSIN II; USEFUL FOR PREVENTION AND REMEDY OF HYPERTENSION, CONGESTIVE HEARTFAILURE, CHRONIC RENAL INSUFFICIENCY, ALDOSTERONISM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0693480-A1 | PYRAZOLE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003757-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING FATTY LIVER DISEASE | SLC5A1, SLC5A2, SLC10A1 | ALDH1A1 85/4885MAPK1 2313/4885RAB9A 3676/4885 |
| US-20090005390-A1 | NOVEL QUINUCLIDINE DERIVATIVES AND THEIR USE | ACHE, CHRNA5, CHRNA3 | ALDH1A1 1095/4885MAPK1 1497/4885RAB9A 1136/4885 |
| US-20050245567-A1 | Novel quinuclidine derivatives and their use | ACHE, CHRNA5, CHRNA3 | ALDH1A1 1095/4885MAPK1 1497/4885RAB9A 1136/4885 |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | PSMB7, PSMA7, PSMB11 | ALDH1A1 2896/4885MAPK1 1758/4885RAB9A 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.