SCHEMBL4624349

SCHEMBL4624349

[c]1c[c]cc(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MAPK1 P28482 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
ATM Q13315 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAOA P21397 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11973060 0.97 ALDH1A1 (0.50) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL195477 0.78 ALDH1A1 (0.53) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27966871 0.77 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27842187 0.77 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL8993020 0.77 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL51203 0.77 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27907683 0.77 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL9213585 0.77
SCHEMBL619546 0.77 ALDH1A1 (0.53) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27385746 0.75 ALDH1A1 (0.50) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110317230-B Phosphate derivatives and use thereof 上海昇悦医药科技有限公司 2023-11-07 CN disclosed
US-11616201-B2 Specific ladder type compounds for organic light emitting devices IDEMITSU KOSAN CO., LTD. (JP) 2023-03-28 US disclosed
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2020-12-03 US disclosed
EP-2626346-B1 BENZO[K]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING SAME IDEMITSU KOSAN CO (JP) 2018-01-10 EP disclosed
CN-102574797-B Benzo [ k ] fluoranthene derivative and organic electroluminescent element containing same 出光兴产株式会社 2017-03-01 CN disclosed
US-9273002-B2 Benzo[k]fluoranthene derivative and organic electroluminescence device containing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-03-01 US disclosed
CN-103403057-B The manufacture method of polyester and fluorine-containing di-carboxylic acid ester cpds ASAHI GLASS CO.,LTD. (JP) 2016-01-20 CN disclosed
US-8703899-B2 Method for producing polyester, and fluorine-containing dicarboxylic acid ester compound ASASHI GLASS COMPANY LIMITED (JP) 2014-04-22 US disclosed
US-20130345387-A1 METHOD FOR PRODUCING POLYESTER, AND FLUORINE-CONTAINING DICARBOXYLIC ACID ESTER COMPOUND ASAHI GLASS COMPANY, LIMITED (JP) 2013-12-26 US disclosed
EP-2626346-A1 BENZO[K]FLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT CONTAINING SAME Idemitsu Kosan Co., Ltd. (JP) 2013-08-14 EP disclosed
US-6586554-B1 Polyarylene and method for production thereof JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-07-01 US disclosed
EP-0773249-B1 Polyphenylene co-polymers MISSISSIPPI POLYMER TECHNOLOGI (US) 2002-10-02 EP disclosed
EP-1234829-A1 SILICON-CONTAINING POLYMERS National Institute of Advanced Industrial Science and Technology (JP) 2002-08-28 EP disclosed
US-6417418-B2 SUCH AS 1,3-PROPENYLIDENE-(1-INDENYL)2 ZIRCONIUM DICHLORIDE; HIGH ACTIVITY, MAKES HIGH MOLECULAR WEIGHT POLYMERS ENICHEM S.P.A. (IT) 2002-07-09 US disclosed
EP-1219657-A1 POLYARYLENE AND METHOD FOR PRODUCTION THEREOF Japan Science and Technology Corporation (JP) 2002-07-03 EP disclosed
US-20010031885-A1 Bridged metallocene complex for the (co) polymerization of olefins ENICHEM S.P.A. (IT) 2001-10-18 US disclosed
US-6211110-B1 Bridged metallocene complex for the (co)polymerization of olefins ENICHEM S.P.A. (IT) 2001-04-03 US disclosed
EP-0955304-A2 Bridged metallocene complex for the (co)polymerization of olefins Enichem S.p.A. (IT) 1999-11-10 EP disclosed
US-5886130-A THE CO-POLYMERS ARE USEFUL AS MOLDING RESINS, AND COMPOSITE MATRIX RESINS, AND WHERE AR IS HETEROARYLENE AS ION EXCHANGE RESINS. MAXDEM INCORPORATED (US) 1999-03-23 US disclosed
EP-0773249-A1 Polyphenylene co-polymers MAXDEM INCORPORATED (US) 1997-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11616201-B2 Specific ladder type compounds for organic light emitting devices APOL1, HMGB2, LOXL1 ALDH1A1 101/4885MAPK1 348/4885TAAR1 1124/4885
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES APOL1, HMGB2, LOXL1 ALDH1A1 101/4885MAPK1 348/4885TAAR1 1124/4885
US-20010031885-A1 Bridged metallocene complex for the (co) polymerization of olefins POF1B, MACF1, HAO2 ALDH1A1 2395/4885MAPK1 2955/4885TAAR1 2334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.