Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807055 | 0.83 | ALDH1A1 (0.51) | HSD17B10NPC1CYP2C9RAB9ANPSR1 | |
| SCHEMBL470698 | 0.81 | SRC (0.57) | SRCALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10920134 | 0.78 | KDM4E (0.55) | HSD17B10NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL27801015 | 0.77 | TPMT (0.49) | HSD17B10NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL9191019 | 0.77 | KDM4E (0.53) | HSD17B10NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL19100974 | 0.77 | HSD17B10 (0.49) | HSD17B10NOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL6291227 | 0.77 | SRC (0.53) | SRCRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL1984171 | 0.77 | HMGB1 (0.55) | SRCHSD17B10CYP2C9NPSR1ALDH1A1 | |
| SCHEMBL29183498 | 0.76 | FBP1 (0.45) | HSD17B10NOTUMCYP2C9RAB9ANPSR1 | |
| SCHEMBL1434189 | 0.76 | HSD17B10 (0.52) | HSD17B10NOTUMALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637431-B2 | Process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl] [(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino] methyl-2-methoxybenzoic acid and its polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2026-05-26 | — | — | US | disclosed |
| EP-4573078-A1 | THIOL ISOMERASES INHIBITORS; PREPARATION THEREOF; AND METHODS OF USE THEREOF | Western New England University (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024039822-A1 | THIOL ISOMERASES INHIBITORS; PREPARATION THEREOF; AND METHODS OF USE THEREOF | WESTERN NEW ENGLAND UNIVERSITY (US) | 2024-02-22 | — | — | WO | disclosed |
| US-20190177281-A1 | PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL] [(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO] METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED (IN) | 2019-06-13 | — | — | US | disclosed |
| WO-2017191650-A1 | PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL][(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO]METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177281-A1 | PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL] [(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO] METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF | CYP1B1, CYP1A1, CYP4B1 | SRC 3023/4885HSD17B10 606/4885NOTUM 3143/4885 |
| US-12637431-B2 | Process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl] [(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino] methyl-2-methoxybenzoic acid and its polymorphs thereof | OPRD1, OPRK1, OPRM1 | SRC 4132/4885HSD17B10 1735/4885NOTUM 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.