Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554194 | 0.91 | PDE5A (0.39) | SLC16A3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL19554333 | 0.83 | AKR1C4 (0.56) | SLC16A3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL19554254 | 0.82 | HDAC3 (0.40) | — | |
| SCHEMBL19554171 | 0.80 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CPTGDR2 | |
| SCHEMBL19554182 | 0.78 | NPC1 (0.42) | DHODHNPC1RAB9AAKR1C4AKR1C3 | |
| SCHEMBL19554215 | 0.76 | SMN1; SMN2 (0.44) | NPC1RAB9AKDM4ECA12CA1 | |
| SCHEMBL19554219 | 0.73 | AKR1C4 (0.48) | NPC1RAB9AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19554266 | 0.73 | KMT2A (0.55) | NPC1RAB9AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19554253 | 0.73 | F11 (0.46) | RAB9AAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554246 | 0.73 | PDE4B (0.44) | PTGDR2NPC1RAB9ANR1H4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |