Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19570245 | 0.88 | NPC1 (0.49) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554171 | 0.85 | PDE5A (0.48) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL19554266 | 0.84 | KMT2A (0.55) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554188 | 0.82 | F11 (0.47) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554253 | 0.82 | F11 (0.46) | PDE4BMEN1PKMKMT2ANPSR1 | |
| SCHEMBL19554136 | 0.81 | MEN1 (0.48) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554190 | 0.79 | KMT2A (0.49) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554218 | 0.77 | MEN1 (0.47) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554231 | 0.77 | KMT2A (0.50) | MEN1PKMKMT2ANPSR1SERPINE1 | |
| SCHEMBL19554178 | 0.76 | NPC1 (0.52) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |