Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | GPR6 | P46095 | 14/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554194 | 0.89 | PDE5A (0.39) | GPR6GRM5 | |
| SCHEMBL19554233 | 0.87 | HDAC3 (0.41) | HDAC3HPGDSGRM5 | |
| SCHEMBL19575819 | 0.85 | JAK2 (0.33) | GPR6GRM5TBK1 | |
| SCHEMBL19554158 | 0.82 | SLC16A3 (0.46) | — | |
| SCHEMBL19554182 | 0.77 | NPC1 (0.42) | — | |
| SCHEMBL19554215 | 0.75 | SMN1; SMN2 (0.44) | GRM5 | |
| SCHEMBL19555237 | 0.73 | NPC1 (0.57) | HDAC3 | |
| SCHEMBL19554219 | 0.73 | AKR1C4 (0.48) | — | |
| SCHEMBL19554178 | 0.72 | NPC1 (0.52) | — | |
| SCHEMBL19575437 | 0.72 | KMO (0.38) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |