Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555065 | 0.80 | GRIK1 (0.43) | KCNMA1CA12CA1CA2CA7 | |
| SCHEMBL19554168 | 0.78 | KCNMA1 (0.43) | KCNMA1ALOX15TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19554229 | 0.77 | SERPINE1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19554313 | 0.73 | KCNMA1 (0.42) | KCNMA1TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL19554946 | 0.69 | F10 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19575738 | 0.69 | TAS1R3 (0.45) | KCNMA1CA12CA1CA2CA7 | |
| SCHEMBL19575815 | 0.68 | F10 (0.44) | KCNMA1CA12CA1CA2CA7 | |
| SCHEMBL19554134 | 0.68 | SERPINE1 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19554200 | 0.68 | GPR35 (0.55) | F10 | |
| SCHEMBL19575737 | 0.67 | KCNMA1 (0.44) | KCNMA1TAS1R3TAS1R1TAS1R2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |