Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554292 | 0.85 | PYGL (0.47) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL19554093 | 0.83 | SMN1; SMN2 (0.62) | KDM4EALDH1A1CYP1A2CYP2C19NPC1 | |
| SCHEMBL19554290 | 0.81 | SMN1; SMN2 (0.47) | KDM4EALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL19554330 | 0.80 | KCNK2 (0.46) | ALDH1A1HDAC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19554145 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL19554338 | 0.78 | SLC16A3 (0.43) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL19554206 | 0.78 | SLC16A3 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL19554215 | 0.78 | SMN1; SMN2 (0.44) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19554249 | 0.78 | ACLY (0.50) | HDAC1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL19554240 | 0.78 | STING1 (0.50) | KDM4EHDAC1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |