Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 10/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118626 | 0.77 | KDM4E (0.68) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19554946 | 0.75 | F10 (0.51) | PRSS12F10NPC1RAB9AMEN1 | |
| SCHEMBL8335663 | 0.72 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19554191 | 0.72 | GAA (0.47) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15283265 | 0.71 | XDH (0.66) | GPR35PRSS12XDHNPC1RAB9A | |
| SCHEMBL19575429 | 0.71 | F10 (0.53) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1307456 | 0.71 | GRIK1 (0.67) | KCNK2PRSS12F10MEN1KMT2A | |
| SCHEMBL19554168 | 0.71 | KCNMA1 (0.43) | GPR35F10NPC1RAB9AALDH1A1 | |
| SCHEMBL19554286 | 0.71 | GAA (0.60) | F10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15283263 | 0.70 | XDH (0.63) | GPR35PRSS12XDHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |