Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 10/20 | 0.45 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184373 | 0.98 | GPR84 (0.47) | CNR2MMP2MMP12MMP9GPR84 | |
| SCHEMBL4550643 | 0.95 | CNR2 (0.44) | CNR2MMP2MMP12MMP9ALDH1A1 | |
| SCHEMBL6912967 | 0.89 | PPARG (0.45) | MMP12ALDH1A1 | |
| SCHEMBL28184358 | 0.85 | CYSLTR2 (0.46) | CNR2ALDH1A1CTRC | |
| SCHEMBL19227459 | 0.85 | LTA4H (0.47) | CNR2ALDH1A1CTRC | |
| SCHEMBL5536701 | 0.83 | LTA4H (0.46) | CNR2ALDH1A1CTRC | |
| SCHEMBL28592584 | 0.83 | LTA4H (0.46) | CNR2ALDH1A1CTRC | |
| SCHEMBL7995558 | 0.83 | LTA4H (0.46) | CNR2ALDH1A1CTRC | |
| SCHEMBL28590813 | 0.83 | LTA4H (0.46) | CNR2ALDH1A1CTRC | |
| SCHEMBL28597219 | 0.83 | LTA4H (0.46) | CNR2ALDH1A1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071547-A1 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2013-03-21 | — | — | US | claimed |
| EP-2509452-A2 | LOW CALORIC FAT REPLACERS | Nestec S.A. (CH) | 2012-10-17 | — | — | EP | claimed |
| WO-2011069958-A2 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2011-06-16 | — | — | WO | claimed |
| EP-2332427-A1 | low caloric fat replacers | Nestec S.A. (CH) | 2011-06-15 | — | — | EP | claimed |
| US-10246470-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2019-04-02 | — | — | US | disclosed |
| US-20180346486-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2018-12-06 | — | — | US | disclosed |
| US-10011609-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2018-07-03 | — | — | US | disclosed |
| CN-104755510-B | Ziegler natta catalyst system of internal donor and preparation method thereof is used as comprising 1,2 phenylene diester | 印度石油有限公司 | 2017-11-07 | — | — | CN | disclosed |
| EP-3068788-A1 | NOVEL HETEROCYCLIC COMPOUNDS | Cadila Healthcare Limited (IN) | 2016-09-21 | — | — | EP | disclosed |
| US-20160257701-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2016-09-08 | — | — | US | disclosed |
| CN-105722841-A | Novel Heterocyclic Compounds | 卡迪拉保健有限公司 | 2016-06-29 | — | — | CN | disclosed |
| WO-2015097713-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2015-07-02 | — | — | WO | disclosed |
| US-20150119399-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2015-04-30 | — | — | US | disclosed |
| EP-2804603-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | President and Fellows of Harvard College (US) | 2014-11-26 | — | — | EP | disclosed |
| WO-2013106547-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-18 | — | — | WO | disclosed |
| US-20130071547-A1 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2013-03-21 | — | — | US | disclosed |
| EP-2509452-A2 | LOW CALORIC FAT REPLACERS | Nestec S.A. (CH) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069958-A2 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2011-06-16 | — | — | WO | disclosed |
| EP-2332427-A1 | low caloric fat replacers | Nestec S.A. (CH) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119399-A1 | BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE | IAPP, GPR119, PCNA | CNR2 3675/4885MMP2 2342/4885MMP12 3307/4885 |
| US-10011609-B2 | Heterocyclic compounds | GPR55, GPR68, GPR65 | CNR2 59/4885MMP2 4855/4885MMP12 4728/4885 |
| US-20180346486-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HK1, HAAO, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CNR2 830/4885MMP2 2936/4885MMP12 3273/4885 |
| US-10246470-B2 | Heterocyclic compounds | HAAO, HK1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CNR2 819/4885MMP2 3006/4885MMP12 3974/4885 |
| US-20160257701-A1 | NOVEL HETEROCYCLIC COMPOUNDS | GPR55, GPR68, GPR65 | CNR2 53/4885MMP2 4842/4885MMP12 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.