SCHEMBL19583249

SCHEMBL19583249

C=CC(=O)NCC(O)C(Br)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 5/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
THRB P10828 1/20 0.36
RAB9A P51151 2/20 0.35
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
BTK Q06187 3/20 0.34
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583251 0.80 MTNR1A (0.47) MTNR1AMTNR1BALDH1A1RAB9AGAA
SCHEMBL19583227 0.76 THRB (0.50) TGM2MTNR1AMTNR1BALDH1A1CYP3A4
SCHEMBL14783698 0.74 CYP2D6 (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19HTT
SCHEMBL9889643 0.71 ALDH1A1 (0.56) TGM2ALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL5490229 0.71 TGM2 (0.45) TGM2MTNR1AMTNR1BALDH1A1CYP3A4
SCHEMBL28717475 0.71 TGM2 (0.48) TGM2MTNR1AMTNR1BALDH1A1CYP3A4
SCHEMBL19583247 0.70 POLB (0.36) MTNR1AMTNR1BALDH1A1SMN1; SMN2
SCHEMBL9472057 0.69 PPARG (0.45) ALDH1A1
SCHEMBL5418397 0.69 THRB (0.51) TGM2MTNR1AMTNR1BALDH1A1CYP3A4
SCHEMBL11757493 0.69 SLC6A4 (0.40) MTNR1AMTNR1BCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226545-B2 Micro injectable, low chromatic aberration intraocular lens materials BENZ RESEARCH AND DEVELOPMENT CORP (US) 2025-02-18 US disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
CN-110891618-B Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2023-01-03 CN disclosed
US-20220249737-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2022-08-11 US disclosed
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
CN-109475660-B Hydrophobic intraocular lenses 宾视研发公司 2022-03-22 CN disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
US-10899862-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-26 US disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
US-20200330643-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2020-10-22 US disclosed
CN-110891618-A Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2020-03-17 CN disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
EP-3458118-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2019-03-27 EP disclosed
US-10196470-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2019-02-05 US disclosed
WO-2018213240-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 WO disclosed
US-20180334520-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 US disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed