Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137246 | 0.88 | FABP3 (0.57) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL19610490 | 0.83 | CA1 (0.46) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL20681236 | 0.77 | FABP3 (0.43) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL19610475 | 0.77 | CA1 (0.61) | GAAGABRA1GABRB2CA1CA2 | |
| SCHEMBL20699064 | 0.74 | KDM4E (0.44) | FABP3FABP4KDM4EGAATHRA | |
| SCHEMBL20698934 | 0.74 | AURKA (0.44) | KDM4EGAATHRATHRB | |
| SCHEMBL20681232 | 0.73 | GABRA1 (0.50) | FABP3FABP4KDM4EGAAGABRA1 | |
| SCHEMBL19475246 | 0.73 | GABRA1 (0.50) | FABP3FABP4KDM4EGAAGABRA1 | |
| SCHEMBL8136292 | 0.73 | FABP4 (0.50) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL19475203 | 0.73 | NLRP3 (0.41) | FABP3FABP4KDM4EGAATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2020-06-11 | — | — | US | disclosed |
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-07-05 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3246022-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179302-A1 | USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, PTGES3, CYP24A1 | FABP3 11/4885FABP4 2616/4885SOAT2 2285/4885 |
| US-10329243-B2 | Biphenyl derivative and uses thereof | PPARD, PCSK9, UGT2B7 | FABP3 15/4885FABP4 258/4885SOAT2 987/4885 |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | FABP3 46/4885FABP4 629/4885SOAT2 1760/4885 |
| US-20180185299-A1 | THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA | PTGER3, CYP24A1, PTGES3 | FABP3 9/4885FABP4 2475/4885SOAT2 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.