SCHEMBL19612487

SCHEMBL19612487

CCCOc1cc(Cl)c(OCCC)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 1/20 0.44
CSNK2A1 P68400 2/20 0.44
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
PKM P14618 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KCNH2 Q12809 1/20 0.39
TLR8 Q9NR97 1/20 0.39
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612241 0.92 L3MBTL1 (0.47) MAPTL3MBTL1HPGDMAPK1CNR1
SCHEMBL19612685 0.89 CNR1 (0.47) MAPTL3MBTL1HPGDMAPK1CNR1
SCHEMBL7461874 0.86 MAPT (0.41) MAPTL3MBTL1HPGDMAPK1CSNK2A1
SCHEMBL29025163 0.84 CNR1 (0.43) MAPTCNR1CNR2KMT2AMEN1
SCHEMBL12603983 0.83 L3MBTL1 (0.44) MAPTL3MBTL1HPGDMAPK1RAB9A
SCHEMBL23271981 0.81 HTT (0.45) MAPTL3MBTL1CNR1CNR2KMT2A
SCHEMBL19612337 0.81 GPR84 (0.46) MAPTL3MBTL1HPGDMAPK1CNR1
SCHEMBL29363872 0.78 ALDH1A1 (0.46) MAPTL3MBTL1HPGDMAPK1CNR1
SCHEMBL487367 0.78 ALDH1A1 (0.46) MAPTL3MBTL1HPGDMAPK1CNR1
SCHEMBL29025217 0.76 CYP2C9 (0.49) MAPTL3MBTL1CNR1CNR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336728-A1 ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF CANON KABUSHIKI KAISHA (JP) 2017-11-23 US disclosed