SCHEMBL1961271

SCHEMBL1961271

NCC(=O)NC(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKACA P17612 2/20 0.70
PLA2G2A P14555 1/20 0.66
MARS1 P56192 1/20 0.64
P2RY1 P47900 4/20 0.64
ADORA1 P30542 3/20 0.64
P2RY2 P41231 3/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
SRC P12931 2/20 0.64
DNPH1 O43598 1/20 0.64
PRKAB2 O43741 1/20 0.64
TRPM2 O94759 1/20 0.64
LDHA P00338 1/20 0.64
ADRB2 P07550 1/20 0.64
FBP1 P09467 1/20 0.64
PRKAG1 P54619 1/20 0.64
PRKAA2 P54646 1/20 0.64
PDE4D Q08499 1/20 0.64
KCNH2 Q12809 1/20 0.64
PRKAA1 Q13131 1/20 0.64
PDE3A Q14432 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6704430 0.88 PRKACA (0.75) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL9295626 0.87 AHCY (0.71) PRKACAMARS1P2RY1ADORA1P2RY2
SCHEMBL9295615 0.87 AHCY (0.71) PRKACAMARS1P2RY1ADORA1P2RY2
SCHEMBL7226454 0.86 HINT1 (0.78) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL3432901 0.86 PRKACA (0.71) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL1000840 0.86 HINT1 (0.78) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL2463542 0.85 PRKACA (0.73) PRKACAMARS1P2RY1ADORA1P2RY2
SCHEMBL1757017 0.85 ADORA1 (0.73) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL19859780 0.85 ADORA1 (0.73) PRKACAPLA2G2AMARS1P2RY1ADORA1
SCHEMBL9426538 0.85 PRKACA (0.73) PRKACAMARS1P2RY1ADORA1P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3387150-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY Novartis AG (CH) 2018-10-17 EP claimed
WO-2017098468-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY NOVARTIS AG (CH) 2017-06-15 WO claimed
WO-2026103936-A1 CHEMICALLY MODIFIED CIRCULAR RNA MOLECULE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海元码智药生物技术有限公司 2026-05-21 WO disclosed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 CN disclosed
EP-4691484-A2 INFLUENZA MRNA VACCINES CureVac SE (DE) 2026-02-11 EP disclosed
US-12508308-B2 Influenza mRNA vaccines CureVac SE (DE) 2025-12-30 US disclosed
US-12492236-B2 Fusion proteins for the treatment of cardiometabolic diseases SHATTUCK LABS, INC. (US) 2025-12-09 US disclosed
WO-2025125630-A1 METHOD FOR BIOPROTAC DESIGN MEDIMMUNE LIMITED (GB) 2025-06-19 WO disclosed
US-20240309346-A1 COMPOSITIONS COMPRISING A VARIANT CAS12I4 POLYPEPTIDE AND USES THEREOF Arbor Biotechnologies, Inc. 2024-09-19 US disclosed
US-20240262881-A1 FUSION PROTEINS FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES SHATTUCK LABS, INC. 2024-08-08 US disclosed
WO-2024151975-A1 DETECTING DEGRADATION OF A POLYNUCLEOTIDE BY RAMAN SPECTROSCOPY LEDNEV IGOR (US) 2024-07-18 WO disclosed
US-20140242154-A1 Compounds, Compositions, Methods, and Kits Relating to Telomere Extension THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-08-28 US disclosed
US-20140242155-A1 Compounds, Compositions, Methods, and Kits Relating to Telomere Extension THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-08-28 US disclosed
WO-2014093924-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2014-06-19 WO disclosed
EP-1200097-B1 METHOD FOR CONTROLLING THE FIDELITY AND THE PROCESSIVITY OF REVERSE TRANSCRIPTASE BY INCORPORATING AND POLYMERISING NUCLEOTIDE ANALOGUES ACCEPTED AS SUBSTRATES OF THE REVERSE TRANSCRIPTION RESPONSE WITHOUT BLOCKING ITS ELONGATION VIGILENT TECHNOLOGIES (FR) 2014-01-08 EP disclosed
WO-2011071931-A2 RNA PREPARATIONS COMPRISING PURIFIED MODIFIED RNA FOR REPROGRAMMING CELLS KARIKO KATALIN (US) 2011-06-16 WO disclosed
US-20110143397-A1 RNA PREPARATIONS COMPRISING PURIFIED MODIFIED RNA FOR REPROGRAMMING CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-06-16 US disclosed
EP-1979364-A2 RNA CONTAINING MODIFIED NUCLEOSIDES AND METHODS OF USE THEREOF The Trustees of The University of Pennsylvania (US) 2008-10-15 EP disclosed
WO-2007024708-A2 RNA CONTAINING MODIFIED NUCLEOSIDES AND METHODS OF USE THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-03-01 WO disclosed
US-6727059-B1 ADMINISTERING A NUCLEOSIDE ANALOG THAT HAS A 3' HYDROXYL GROUP LOCATED ON THE C3' CARBON OF THE 2'-DEOXYRIBOSE, FOR EXAMPLE DUTP; FOR RETROID VIRUS INFECTIONS SUCH AS HIV; MIXTURE WITH REVERSE TRANSCRIPTASE INHIBITORS SUCH AS AZT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508308-B2 Influenza mRNA vaccines RNMT, RNGTT, AMPD3 PRKACA 1983/4885PLA2G2A 589/4885MARS1 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.