Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 3/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987408 | 0.90 | PKM (0.57) | PKMMAPK1RAB9ANPC1FPR2 | |
| SCHEMBL23453327 | 0.86 | PKM (0.69) | PKMMAPK1RAB9ANPC1FPR2 | |
| SCHEMBL18844837 | 0.82 | ENPP2 (0.55) | PKMMAPK1GAAEPHX1MEN1 | |
| SCHEMBL19612837 | 0.81 | MAPK1 (0.52) | PKMMAPK1GAAMEN1KMT2A | |
| SCHEMBL10596369 | 0.79 | ENPP2 (0.59) | MAPK1EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL19612839 | 0.79 | PYGL (0.49) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL17672410 | 0.77 | PKM (0.45) | PKMMAPK1POLBALDH1A1 | |
| SCHEMBL20862403 | 0.76 | TAS1R3 (0.57) | PKMMAPK1RAB9ANPC1FPR2 | |
| SCHEMBL12407169 | 0.75 | RAB9A (0.73) | PKMMAPK1RAB9ANPC1FPR2 | |
| SCHEMBL24697454 | 0.75 | EPHX1 (0.46) | MAPK1EPHX1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335071-A1 | COMPOSITION CONTAINING BIS-UREAS FOR FORMING STABLE GELS | SORBONNE UNIVERSITE (FR) | 2017-11-23 | — | — | US | disclosed |