Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762937 | 0.95 | THRB (0.91) | THRBTHRA | |
| SCHEMBL22106256 | 0.95 | THRB (0.91) | THRBTHRA | |
| SCHEMBL30763153 | 0.93 | THRB (0.87) | THRBTHRA | |
| SCHEMBL22100229 | 0.93 | THRB (0.87) | THRBTHRA | |
| SCHEMBL22106076 | 0.92 | THRB (0.85) | THRBTHRA | |
| SCHEMBL30763059 | 0.92 | THRB (0.85) | THRBTHRA | |
| SCHEMBL29977021 | 0.91 | THRB (0.83) | THRBTHRA | |
| SCHEMBL22106066 | 0.90 | THRB (0.80) | THRBTHRA | |
| SCHEMBL22106080 | 0.90 | THRB (0.80) | THRBTHRA | |
| SCHEMBL30762989 | 0.90 | THRB (0.80) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425437-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-12-26 | — | — | US | disclosed |
| EP-4333844-A1 | FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS | Autobahn Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| CN-117597122-A | Fatty Acid Amide Hydrolase (FAAH) cleavable prodrugs of thyromimetics and combinations with peripherally restricted FAAH inhibitors | 速通医疗公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20230348364-A1 | ISOTOPIC THYROMIMETIC COMPOUNDS | AUTOBAHN THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348364-A1 | ISOTOPIC THYROMIMETIC COMPOUNDS | AUTOBAHN THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348364-A1 | ISOTOPIC THYROMIMETIC COMPOUNDS | AUTOBAHN THERAPEUTICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230048992-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-02-16 | — | — | US | disclosed |
| US-11578032-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-02-14 | — | — | US | disclosed |
| WO-2022236133-A1 | FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS | AUTOBAHN THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022236133-A1 | FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF THYROMIMETICS AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS | AUTOBAHN THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-20210002208-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-01-07 | — | — | US | disclosed |
| US-10870616-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-12-22 | — | — | US | disclosed |
| US-10870616-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200325092-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-10-15 | — | — | US | disclosed |
| US-20200325092-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-10-15 | — | — | US | disclosed |
| US-10544075-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-01-28 | — | — | US | disclosed |
| WO-2019160980-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-08-22 | — | — | WO | disclosed |
| US-20190210950-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-07-11 | — | — | US | disclosed |
| EP-3457851-A1 | DERIVATIVES OF SOBETIROME | Oregon Health & Science University (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017201320-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348364-A1 | ISOTOPIC THYROMIMETIC COMPOUNDS | TPO, THOP1, TSHR | THRB 6/4885THRA 7/4885 |
| US-10870616-B2 | Derivatives of sobetirome | SNCA, SLC6A3, SLC6A1 | THRB 2754/4885THRA 2915/4885 |
| US-20230048992-A1 | NOVEL THYROMIMETICS | TSHR, TPO, CHRM1 | THRB 9/4885THRA 8/4885 |
| US-20200325092-A1 | DERIVATIVES OF SOBETIROME | SNCA, SLC6A3, SLC6A1 | THRB 2754/4885THRA 2915/4885 |
| US-20210002208-A1 | DERIVATIVES OF SOBETIROME | SLC6A3, TPH1, SLC6A2 | THRB 149/4885THRA 213/4885 |
| US-20190210950-A1 | DERIVATIVES OF SOBETIROME | SNCA, SLC6A3, SLC6A1 | THRB 2754/4885THRA 2915/4885 |
| US-20240425437-A1 | DERIVATIVES OF SOBETIROME | SNCA, SLC6A3, SLC6A1 | THRB 2754/4885THRA 2915/4885 |
| US-10544075-B2 | Derivatives of sobetirome | SNCA, SLC6A3, SLC6A1 | THRB 2754/4885THRA 2915/4885 |
| US-11578032-B2 | Derivatives of sobetirome | SLC6A3, TPH1, SLC6A2 | THRB 149/4885THRA 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.