Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622283 | 0.75 | MAPT (0.45) | MAPTLMNAL3MBTL1 | |
| SCHEMBL19622288 | 0.74 | CYP4F2 (0.41) | MAPTALDH1A1CA1CA2LMNA | |
| SCHEMBL19622328 | 0.73 | PDE4B (0.44) | MAPTRAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL17787354 | 0.71 | KDM4E (0.44) | ALDH1A1KDM4E | |
| SCHEMBL3221698 | 0.70 | HPGDS (0.58) | MAPTRAB9AGAAALDH1A1MAPK1 | |
| SCHEMBL19622337 | 0.70 | LMNA (0.50) | MAPTGAAALDH1A1P2RX3MAPK1 | |
| SCHEMBL26606546 | 0.70 | MAPT (0.54) | MAPTRAB9AGAAALDH1A1CA1 | |
| SCHEMBL19622338 | 0.69 | LMNA (0.49) | MAPTGAAALDH1A1P2RX3MAPK1 | |
| SCHEMBL19622327 | 0.69 | CA12 (0.44) | GAAALDH1A1CA1CA2SMN1; SMN2 | |
| SCHEMBL4598308 | 0.69 | ALDH1A1 (0.58) | MAPTRAB9AGAAALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |