Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622288 | 0.84 | CYP4F2 (0.41) | MAPTOPRM1OPRD1OPRK1HRH3 | |
| SCHEMBL19622328 | 0.82 | PDE4B (0.44) | MAPTL3MBTL1OPRM1OPRD1LMNA | |
| SCHEMBL19622200 | 0.75 | MAPT (0.40) | MAPTL3MBTL1LMNA | |
| SCHEMBL4260035 | 0.74 | TSHR (0.59) | MAPTADRB1ADRB3L3MBTL1OPRM1 | |
| SCHEMBL13183817 | 0.72 | MAPT (0.54) | MAPTADRB1ADRB3L3MBTL1OPRM1 | |
| SCHEMBL15933217 | 0.71 | LTA4H (0.50) | — | |
| SCHEMBL1271501 | 0.71 | MAPT (0.57) | MAPTL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL19622337 | 0.71 | LMNA (0.50) | MAPTL3MBTL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8017433 | 0.71 | OPRM1 (0.52) | MAPTADRB1ADRB3OPRM1OPRD1 | |
| SCHEMBL6180315 | 0.70 | MAPT (0.57) | MAPTL3MBTL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |