Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ATP4A | P20648 | 3/20 | 0.47 |
| ▸ | ATP4B | P51164 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626484 | 0.86 | TSHR (0.57) | RECQLTSHRPRMT6KDM4EALDH1A1 | |
| SCHEMBL19625340 | 0.85 | CYP19A1 (0.44) | RECQLTSHRPRMT6KDM4EALDH1A1 | |
| SCHEMBL19626566 | 0.82 | ATP4A (0.65) | RECQLGAAKDM4EALDH1A1POLB | |
| SCHEMBL201741 | 0.81 | CYP19A1 (0.63) | RECQLTSHRPRMT6GAAALDH1A1 | |
| SCHEMBL3052495 | 0.77 | PRMT6 (0.69) | RECQLTSHRPRMT6GAAKDM4E | |
| SCHEMBL19626579 | 0.76 | SCN9A (0.67) | RECQLTSHRPRMT6GAAKDM4E | |
| SCHEMBL3715239 | 0.75 | ALDH1A1 (0.64) | RECQLGAAALDH1A1 | |
| SCHEMBL13591290 | 0.74 | HTT (0.50) | RECQLTSHRPRMT6GAAKDM4E | |
| SCHEMBL8700799 | 0.74 | KDM4E (0.68) | RECQLTSHRPRMT6GAAKDM4E | |
| SCHEMBL3322009 | 0.74 | HSD17B1 (0.68) | RECQLTSHRPRMT6GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | RECQL 1370/4885TSHR 1830/4885PRMT6 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.