SCHEMBL196266

SCHEMBL196266

C=C(C)C(=O)NCCOC(=O)CC#N

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.36
THRB P10828 1/20 0.32
LMNA P02545 2/20 0.30
MEN1 O00255 1/20 0.30
MITF O75030 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
MDM2 Q00987 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379689 0.81 ADRA2A (0.41) THRBMEN1ALDH1A1KMT2A
SCHEMBL2200440 0.80 THRB (0.52) MCL1THRBALDH1A1
SCHEMBL30389957 0.80 NAAA (0.41) THRBMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL196382 0.80 MGAM (0.40) THRBMEN1ALDH1A1KMT2A
SCHEMBL13112972 0.78 MGAM (0.34) THRBMEN1ALDH1A1MAPK1KMT2A
SCHEMBL23064187 0.77 THRB (0.38) THRBMEN1ALDH1A1MAPK1KMT2A
SCHEMBL553241 0.77 ALDH1A1 (0.43) THRBLMNAMEN1ALDH1A1MAPK1
SCHEMBL16805859 0.77 THRB (0.47) THRBMEN1ALDH1A1KMT2A
SCHEMBL20541917 0.77 DGKA (0.43) THRBALDH1A1
SCHEMBL12338862 0.77 TSHR (0.45) THRBLMNAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214640-B2 Processing aids and polymer formulations containing the same and method for producing the same ROHM AND HAAS COMPANY (US) 2022-01-04 US claimed
US-11168205-B2 Composite polymer modifiers ARKEMA INC. (US) 2021-11-09 US claimed
US-9908958-B2 Processing aids and polymer formulations containing the same and method for producing the same ROHM AND HAAS COMPANY (US) 2018-03-06 US claimed
EP-2797961-B1 PROCESSING AIDS AND POLYMER FORMULATIONS CONTAINING THE SAME AND METHOD FOR PRODUCING THE SAME ROHM & HAAS (US) 2017-10-04 EP claimed
US-9309397-B2 Processing aids and polymer formulations containing the same and method for producing the same ROHM AND HAAS COMPANY (US) 2016-04-12 US claimed
US-20140371396-A1 Processing Aids and Polymer Formulations Containing the Same and Method for Producing the Same ROHM AND HAAS COMPANY 2014-12-18 US claimed
EP-2797961-A1 PROCESSING AIDS AND POLYMER FORMULATIONS CONTAINING THE SAME AND METHOD FOR PRODUCING THE SAME Rohm and Haas Company (US) 2014-11-05 EP claimed
US-8722750-B2 Polymer composition ROHM AND HAAS COMPANY (US) 2014-05-13 US claimed
WO-2013100997-A1 PROCESSING AIDS AND POLYMER FORMULATIONS CONTAINING THE SAME AND METHOD FOR PRODUCING THE SAME ROHM AND HAAS COMPANY (US) 2013-07-04 WO claimed
US-20120208963-A1 PROCESSING AIDS AND POLYMER FORMULATIONS CONTAINING THE SAME AND METHOD FOR PRODUCING THE SAME ROHM AND HAAS CHEMICALS LLC 2012-08-16 US claimed
EP-2045290-B1 Improved polymer composition ROHM & HAAS (US) 2010-05-12 EP claimed
US-20090093560-A1 Polymer composition ROHM AND HAAS COMPANY 2009-04-09 US claimed
US-20220389207-A1 ONE-PACK POLYMER MODIFIERS ARKEMA FRANCE (FR) 2022-12-08 US disclosed
US-11214640-B2 Processing aids and polymer formulations containing the same and method for producing the same ROHM AND HAAS COMPANY (US) 2022-01-04 US disclosed
US-11168205-B2 Composite polymer modifiers ARKEMA INC. (US) 2021-11-09 US disclosed
EP-3688112-A1 ONE-PACK POLYMER MODIFIERS Arkema Inc. (US) 2020-08-05 EP disclosed
WO-2010099160-A1 COMPOSITE POLYMER MODIFIERS ARKEMA INC. (US) 2010-09-02 WO disclosed
US-20090093560-A1 Polymer composition ROHM AND HAAS COMPANY 2009-04-09 US disclosed
US-7144605-B2 Curable coating composition and coating film forming method NIPPON PAINT CO., LTD. (JP) 2006-12-05 US disclosed
US-20040219381-A1 Curable coating composition and coating film forming method NIPPON PAINT CO., LTD. 2004-11-04 US disclosed