SCHEMBL2200440

SCHEMBL2200440

C=C(C)C(=O)OCCOC(=O)CC#N

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 4/20 0.46
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.37
MCL1 Q07820 3/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846107 0.93 TSHR (0.51) THRBTSHRPOLBAPEX1HTT
SCHEMBL17142026 0.91 TSHR (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL15249368 0.83 THRB (0.53) THRBTSHRPOLBAPEX1HTT
SCHEMBL18854249 0.82 THRB (0.49) THRBTSHRPOLBAPEX1HTT
Water SCHEMBL1765013 0.82 THRB (0.71) THRBTSHRPOLBAPEX1HTT
SCHEMBL6890414 0.82 MCL1 (0.43) TDP1MCL1MAPTBLM
SCHEMBL10901343 0.80 ALDH1A1 (0.45) TSHRHTTALDH1A1MCL1CHRM5
SCHEMBL7758566 0.80 THRB (0.63) THRBTSHRPOLBAPEX1HTT
SCHEMBL196266 0.80 MCL1 (0.36) THRBALDH1A1MCL1
SCHEMBL2723137 0.80 TSHR (0.49) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110229549-B High-temperature-resistant insulating composition, insulating coating, and preparation method and application thereof 全球能源互联网研究院有限公司 2021-05-18 CN claimed
US-7560519-B2 Dual-stage wafer applied underfills LORD CORPORATION (US) 2009-07-14 US claimed
EP-0492210-B1 Polymer-coated concrete BASF AG (DE) 1994-09-21 EP claimed
US-5215827-A Acrylic amide or ester copolymers BASF AKTIENGESELLSCHAFT (DE) 1993-06-01 US claimed
US-5213901-A Paint binder containing a film former and polymeric composition ROHM AND HAAS COMPANY (US) 1993-05-25 US claimed
US-5066376-A Crosslinked Acrylamide Type Gel Medium EASTMAN KODAK COMPANY (US) 1991-11-19 US claimed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP claimed
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-12 US disclosed
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-12595371-B2 Contact lens with improved vision break-up time JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
EP-4707342-A2 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES Johnson & Johnson Vision Care, Inc. (US) 2026-03-11 EP disclosed
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2026-02-12 US disclosed
US-12534623-B2 Contact lens with improved tear film optical quality JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-01-27 US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 US disclosed
US-4201589-A ACRYLIC ESTER POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1980-05-06 US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-4133687-A Photographic elements having hydrophilic colloid layers containing compounds having activator precursors and hydrophobic developing agents uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1979-01-09 US disclosed
US-4125636-A Desensitizing composition and desensitizing method FUJI PHOTO FILM CO., LTD. (JP) 1978-11-14 US disclosed
US-4065435-A OXIDATION-REDUCTION PROPERTIES, ACRYLIC FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-4054722-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light NLRP3, NLRP1, XDH THRB 372/4885TSHR 980/4885POLB 1817/4885
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES NECTIN4, CRYAB, PSEN1 THRB 2635/4885TSHR 3224/4885POLB 4496/4885
US-12595371-B2 Contact lens with improved vision break-up time CUTA, VEGFA, CASP14 THRB 976/4885TSHR 3672/4885POLB 1961/4885
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light CRY1, SCNN1G, MALT1 THRB 424/4885TSHR 832/4885POLB 2120/4885
US-12534623-B2 Contact lens with improved tear film optical quality CUTA, CRYAA, TCOF1 THRB 1083/4885TSHR 1988/4885POLB 1971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.