Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL28077918 | 1.00 | GPR84 (0.47) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL28496754 | 1.00 | GPR84 (0.47) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27714853 | 0.93 | L3MBTL1 (0.35) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1248113 | 0.93 | L3MBTL1 (0.35) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28087493 | 0.91 | L3MBTL1 (0.36) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL15955680 | 0.87 | L3MBTL1 (0.33) | TDP1KMT2AMEN1 | |
| Dioxane SCHEMBL28234971 | 0.84 | HTT (0.36) | TSHRTDP1KMT2AMEN1LMNA | |
| SCHEMBL28234972 | 0.83 | L3MBTL1 (0.31) | TDP1KMT2AMEN1 | |
| Palmitic Acid SCHEMBL15659528 | 0.79 | GPR84 (0.49) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3382769 | 0.78 | CPB2 (0.35) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337870-B2 | Low toxicity topical active agent delivery system | YOUNG PHARMACEUTICALS, INC. (US) | 2012-12-25 | — | — | US | claimed |
| CN-111973507-A | External-use skin ointment and preparation method thereof | 杨军 | 2020-11-24 | — | — | CN | disclosed |
| US-20180161435-A1 | Low Toxicity Topical Active Agent Delivery System | KULESZA JOHN E (US) | 2018-06-14 | — | — | US | disclosed |
| EP-2512458-B1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | KULESZA JOHN E (US) | 2016-05-18 | — | — | EP | disclosed |
| US-20150320867-A1 | TOPICAL FORMULATIONS AND METHODS FOR THE USE THEREOF | COTY INC. (US) | 2015-11-12 | — | — | US | disclosed |
| WO-2014116653-A1 | TOPICAL FORMULATIONS AND METHODS FOR THE USE THEREOF | COTY INC. (US) | 2014-07-31 | — | — | WO | disclosed |
| WO-2014066225-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | KULESZA JOHN E (US) | 2014-05-01 | — | — | WO | disclosed |
| US-20130310355-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | YOUNG PHARMACEUTICALS INC (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130096203-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | YOUNG PHARMACEUTICALS, INC. (US) | 2013-04-18 | — | — | US | disclosed |
| US-8337870-B2 | Low toxicity topical active agent delivery system | YOUNG PHARMACEUTICALS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| EP-2512458-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | Kulesza, John E. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011081672-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | KULESZA JOHN E (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110142769-A1 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM | KULESZA JOHN E | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320867-A1 | TOPICAL FORMULATIONS AND METHODS FOR THE USE THEREOF | CUTA, TSLP, MMP8 | GPR84 1726/4885PPARG 679/4885PPARD 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.