Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634642 | 0.86 | DRD3 (0.50) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL21015335 | 0.85 | LMNA (0.46) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634720 | 0.82 | LMNA (0.48) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634724 | 0.82 | LOXL2 (0.53) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634647 | 0.79 | LMNA (0.48) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634815 | 0.74 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634458 | 0.74 | KMT2A (0.48) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL19910574 | 0.72 | MEP1B (0.64) | KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL19634640 | 0.72 | LMNA (0.53) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL19634410 | 0.72 | DRD2 (0.50) | MEN1KMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |