Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MYOC | Q99972 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171227 | 0.78 | NPC1 (0.58) | GAAMGLLMAPTNPC1RAB9A | |
| SCHEMBL3080087 | 0.73 | RAB9A (0.67) | GAAMGLLMAPTNPC1RAB9A | |
| SCHEMBL20971726 | 0.72 | MGLL (0.47) | GAAMGLLATMBCL9CTNNB1 | |
| SCHEMBL2440741 | 0.72 | ALDH1A1 (0.49) | GAAMGLLATMNR1H4BCL9 | |
| SCHEMBL21479385 | 0.72 | NPC1 (0.47) | GAAMGLLATMBCL9CTNNB1 | |
| SCHEMBL1733955 | 0.71 | MGLL (0.57) | GAAMGLLNR1H4BCL9CTNNB1 | |
| SCHEMBL3573967 | 0.71 | MAPT (0.66) | GAAMGLLATMMAPTNPC1 | |
| SCHEMBL29708145 | 0.71 | GAA (0.50) | GAAMGLLATMBCL9CTNNB1 | |
| SCHEMBL16862865 | 0.70 | NPC1 (0.47) | GAAMGLLATMBCL9CTNNB1 | |
| SCHEMBL2477935 | 0.70 | NPC1 (0.57) | MGLLMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653143-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-19 | — | — | US | disclosed |
| EP-3215502-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-24 | — | — | EP | disclosed |
| US-20170339954-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170339954-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, HDHD5 | GAA 1275/4885MGLL 1946/4885ATM 4450/4885 |
| US-10653143-B2 | Herbicidal compounds | DDT, HAX1, HDHD5 | GAA 1275/4885MGLL 1946/4885ATM 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.