Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL22749436 | 1.00 | — | — | |
| SCHEMBL20424315 | 0.97 | — | — | |
| SCHEMBL9011349 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL11074725 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL11074722 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL11074727 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL11072730 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL11072733 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL9011352 | 0.95 | ALDH1A1 (0.95) | ALDH1A1ALOX15KDM4EGAAMAPT | |
| SCHEMBL9065253 | 0.89 | ALDH1A1 (0.83) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255045-A1 | SYSTEM AND METHOD FOR ACHIEVING A ONE COMPONENT GROWABLE RESIN SYSTEM | DAVIES ROBERT MICHAEL (US) | 2020-12-24 | — | — | WO | claimed |
| US-10711157-B2 | Composition for window film, flexible window film formed therefrom, and flexible display device comprising same | SAMSUNG SDI CO., LTD. (KR) | 2020-07-14 | — | — | US | disclosed |
| US-10611925-B2 | Composition for window film, flexible window film formed therefrom, and flexible display device comprising same | SAMSUNG SDI CO., LTD. (KR) | 2020-04-07 | — | — | US | disclosed |
| US-10563092-B2 | Composition for window film, flexible window film formed therefrom, and flexible display device comprising same | SAMSUNG SDI CO., LTD. (KR) | 2020-02-18 | — | — | US | disclosed |
| US-10450482-B2 | Composition for window film, flexible window film formed therefrom, and flexible display device comprising same | SAMSUNG SDI CO., LTD. (KR) | 2019-10-22 | — | — | US | disclosed |
| US-10329385-B2 | Composition for window film, flexible window film formed therefrom, and flexible display device comprising same | SAMSUNG SDI CO., LTD. (KR) | 2019-06-25 | — | — | US | disclosed |
| US-20190023860-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND DISPLAY DEVICE COMPRISING SAME | SAMSUNG SDI CO., LTD. (KR) | 2019-01-24 | — | — | US | disclosed |
| US-20180355175-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | Solip Tech Co., Ltd. (KR) | 2018-12-13 | — | — | US | disclosed |
| US-20180282484-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-10-04 | — | — | US | disclosed |
| US-20180244953-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-08-30 | — | — | US | disclosed |
| US-20180215948-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-08-02 | — | — | US | disclosed |
| CN-107849357-A | Composition for fenestrated membrane, the pliability fenestrated membrane formed by the composition and the flexible display device for including the pliability fenestrated membrane | 三星SDI株式会社 | 2018-03-27 | — | — | CN | disclosed |
| US-20170349787-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |
| US-20170349786-A1 | COMPOSITION FOR WINDOW FILM, FLEXIBLE WINDOW FILM FORMED THEREFROM, AND FLEXIBLE DISPLAY DEVICE COMPRISING SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-12-07 | — | — | US | disclosed |
| CN-107108898-A | Composition for window film, flexible window film formed therefrom, and flexible display device including the same | 三星SDI株式会社 | 2017-08-29 | — | — | CN | disclosed |