Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464406 | 0.87 | MAPT (0.65) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL21708007 | 0.84 | CYP1A2 (0.55) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL21708021 | 0.82 | MAPT (0.68) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL4789312 | 0.82 | SMN1; SMN2 (0.69) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL2831045 | 0.81 | L3MBTL1 (0.62) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL9647639 | 0.81 | CYP1A2 (0.54) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL21708015 | 0.81 | MAPT (0.67) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL21708013 | 0.81 | MAPT (0.67) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL525606 | 0.81 | MAOA (0.64) | MAPTNPSR1TDP1LMNAKDM4E | |
| SCHEMBL21708008 | 0.81 | KDM1A (0.67) | MAPTNPSR1TDP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195966-B | Microbiocidal thiazole derivatives | 先正达参股股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| EP-3464284-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-21 | — | — | EP | disclosed |
| US-20200277288-A1 | Microbiocidal Thiazole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-03 | — | — | US | disclosed |
| US-10662182-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20190330168-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |
| EP-3464284-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| CN-109195966-A | Kill the thiazole of microorganism | 先正达参股股份有限公司 | 2019-01-11 | — | — | CN | disclosed |
| WO-2017207362-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277288-A1 | Microbiocidal Thiazole Derivatives | MSR1, CASP1, TLR1 | MAPT 4103/4885NPSR1 2681/4885TDP1 836/4885 |
| US-20190330168-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | MSR1, CASP1, MPO | MAPT 4152/4885NPSR1 2831/4885TDP1 1066/4885 |
| US-10662182-B2 | Microbiocidal thiazole derivatives | MSR1, CASP1, MPO | MAPT 4152/4885NPSR1 2831/4885TDP1 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.