Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.58 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889290 | 0.94 | GAA (0.65) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL20889278 | 0.85 | ALOX5 (0.63) | GAAALDH1A1KDM4EGFERHPGD | |
| SCHEMBL5165739 | 0.84 | ALOX5 (0.65) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL1968827 | 0.81 | ADORA1 (0.60) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL7975156 | 0.81 | ADORA1 (0.81) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL5167267 | 0.81 | ALOX5 (0.65) | ADORA1GAAALDH1A1KDM4EHPGD | |
| SCHEMBL6279815 | 0.80 | PKM (0.49) | GAAALDH1A1KDM4EGFERHPGD | |
| SCHEMBL2986663 | 0.80 | ADORA1 (0.79) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL13464259 | 0.79 | ADORA1 (0.57) | ADORA1GAAALDH1A1KDM4EGFER | |
| SCHEMBL20889753 | 0.79 | SALL4 (0.56) | GAAALDH1A1KDM4EGFERHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102548-A | Cu-W 2 Method for preparing imidazole pyridine compound by using C/AC catalytic lignin and beta-O-4 model compound | 中国科学院大连化学物理研究所 | 2023-05-12 | — | — | CN | claimed |
| EP-1218382-B1 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-01-28 | — | — | EP | claimed |
| US-6638933-B2 | Analgesics | GRUENENTHAL GMBH (DE) | 2003-10-28 | — | — | US | claimed |
| JP-2003511451-A | — | — | 2003-03-25 | — | — | JP | claimed |
| US-20030018032-A1 | Bicyclic imidazo-3-yl-amine derivatives | GRUENENTHAL GMBH | 2003-01-23 | — | — | US | claimed |
| EP-1218382-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001027111-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | claimed |
| CN-116102548-A | Cu-W 2 Method for preparing imidazole pyridine compound by using C/AC catalytic lignin and beta-O-4 model compound | 中国科学院大连化学物理研究所 | 2023-05-12 | — | — | CN | disclosed |
| US-11530209-B2 | Small molecule inhibition of transcription factor SALL4 and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20200317664-A1 | SMALL MOLECULE INHIBITION OF TRANSCRIPTION FACTOR SALL4 AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-08 | — | — | US | disclosed |
| WO-2019070943-A1 | SMALL MOLECULE INHIBITION OF TRANSCRIPTION FACTOR SALL4 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-11 | — | — | WO | disclosed |
| EP-2334675-B1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2014-03-26 | — | — | EP | disclosed |
| EP-2334675-B1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2014-03-26 | — | — | EP | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |
| EP-1218382-B1 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-6638933-B2 | Analgesics | GRUENENTHAL GMBH (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030018032-A1 | Bicyclic imidazo-3-yl-amine derivatives | GRUENENTHAL GMBH | 2003-01-23 | — | — | US | disclosed |
| EP-1218382-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001027111-A2 | BICYCLIC IMIDAZO-3-YL-AMINE DERIVATIVES | Grünenthal GmbH (DE) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530209-B2 | Small molecule inhibition of transcription factor SALL4 and uses thereof | SALL4, GLI2, TCF4 | ADORA1 4585/4885GAA 3761/4885ALDH1A1 1038/4885 |
| US-20030018032-A1 | Bicyclic imidazo-3-yl-amine derivatives | OPRK1, IPO4, GRIN3A | ADORA1 330/4885GAA 3278/4885ALDH1A1 1244/4885 |
| US-20200317664-A1 | SMALL MOLECULE INHIBITION OF TRANSCRIPTION FACTOR SALL4 AND USES THEREOF | SALL4, GLI2, TCF4 | ADORA1 4585/4885GAA 3761/4885ALDH1A1 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.