Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670214 | 0.83 | TRPA1 (0.38) | KDM1AMTORKMOCNR2LMNA | |
| SCHEMBL19670209 | 0.83 | CNR2 (0.36) | KDM1AMTORCNR2LMNACHRM5 | |
| SCHEMBL17618384 | 0.82 | USP2 (0.40) | KDM1ATRPV1KCNH2UCHL1KMO | |
| SCHEMBL16775856 | 0.82 | TRPV1 (0.39) | KDM1ATRPV1KCNH2UCHL1KMO | |
| SCHEMBL19670579 | 0.81 | TRPA1 (0.36) | KDM1ATRPV1CHRM5MEN1KMT2A | |
| SCHEMBL19670179 | 0.81 | HTR2C (0.46) | TRPV1TSHRMEN1KMT2AUBE2M | |
| SCHEMBL19670221 | 0.81 | UBE2M (0.37) | KDM1AMTORPOLBMEN1KMT2A | |
| SCHEMBL19670141 | 0.81 | SCN9A (0.37) | KDM1ATRPV1POLBLMNATSHR | |
| SCHEMBL19670135 | 0.80 | MEN1 (0.41) | KDM1ATRPV1KMOLMNATSHR | |
| SCHEMBL19670412 | 0.80 | POLB (0.37) | KDM1ACNR2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |