Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17618861 | 0.86 | TRPV1 (0.45) | TRPV1MKNK1CNR2WNT3AUCHL1 | |
| SCHEMBL19670497 | 0.84 | MAPT (0.45) | TRPV1KDRMAPT | |
| SCHEMBL19670299 | 0.83 | FYN (0.43) | TRPV1MAPTMAPK1 | |
| SCHEMBL19670573 | 0.83 | MAPK10 (0.39) | WNT3AMAPK1 | |
| SCHEMBL19365413 | 0.81 | ADCY1 (0.50) | MAPK1 | |
| SCHEMBL19670440 | 0.80 | CA12 (0.42) | CNR2KMO | |
| SCHEMBL19670556 | 0.79 | ADCY1 (0.43) | MAPTMAPK1 | |
| SCHEMBL17624593 | 0.79 | TRPV1 (0.40) | TRPV1CNR2KMO | |
| SCHEMBL19670466 | 0.78 | CA2 (0.41) | TRPV1MAPT | |
| SCHEMBL19365574 | 0.78 | CA2 (0.41) | TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |