Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 5/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19706124 | 0.90 | MGLL (0.45) | MGLLPTGESDCUN1D1UBE2MPOLB | |
| SCHEMBL19365557 | 0.89 | MGLL (0.40) | MGLLPTGESDCUN1D1EPHB4BTK | |
| SCHEMBL19706296 | 0.87 | POLB (0.39) | DCUN1D1UBE2MEPHB4POLBRAB9A | |
| SCHEMBL19670547 | 0.79 | MGLL (0.39) | MGLLPTGESEPHB4BTKRAF1 | |
| SCHEMBL16249968 | 0.78 | MGLL (0.39) | MGLLPTGESDCUN1D1UBE2MEPHB4 | |
| SCHEMBL19365784 | 0.77 | POLB (0.47) | DCUN1D1UBE2MPOLBRAB9A | |
| SCHEMBL19365828 | 0.76 | CA12 (0.46) | DCUN1D1VCP | |
| SCHEMBL19365722 | 0.76 | POLB (0.41) | DCUN1D1VCPUBE2MPOLBRAB9A | |
| SCHEMBL19670560 | 0.75 | POLB (0.47) | POLBRAB9A | |
| SCHEMBL19365835 | 0.75 | CNR2 (0.53) | DCUN1D1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |