SCHEMBL19681509

SCHEMBL19681509

CCCCCCCCCCCCC(CN(CCC[N+](C)(C)CCCS(=O)(=O)[O-])CC(CCCCCCCCCCCC)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 2/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
GRK2 P25098 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19681591 0.89 BBOX1 (0.39) BBOX1MEN1LMNAPOLBGRK2
SCHEMBL19681581 0.82 ADRA1D (0.37) BBOX1
SCHEMBL25681562 0.79 GLS2 (0.35) BBOX1
SCHEMBL19681511 0.79 BBOX1 (0.44) BBOX1
SCHEMBL24787486 0.78 DNM1 (0.31)
SCHEMBL19681510 0.76 TLR2 (0.31) LMNA
SCHEMBL30511241 0.76 BBOX1 (0.45) BBOX1
SCHEMBL19681644 0.75 MEN1 (0.32) BBOX1MEN1LMNAPOLBGRK2
SCHEMBL26726087 0.75 SMN1; SMN2 (0.42) MEN1LMNAKMT2A
SCHEMBL25681505 0.72 PSMD14 (0.42) BBOX1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685710-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-06-27 US disclosed
US-11542229-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-01-03 US disclosed
US-20210395192-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-12-23 US disclosed
US-20200140378-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-05-07 US disclosed
US-10562849-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-02-18 US disclosed
US-20170349543-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349543-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885
US-10562849-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885
US-11685710-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885
US-11542229-B2 Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885
US-20200140378-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885
US-20210395192-A1 CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS ABHD16A, AARS1, CFTR BBOX1 3301/4885MEN1 2129/4885LMNA 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.