Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189345 | 0.81 | DAO (0.46) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL19681864 | 0.80 | MEN1 (0.47) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL20132015 | 0.77 | RAB9A (0.50) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL19681866 | 0.76 | L3MBTL1 (0.42) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL10661141 | 0.75 | SLC6A4 (0.53) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL22602000 | 0.74 | SAE1 (0.46) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL11601101 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL19681869 | 0.72 | MEN1 (0.41) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL19681872 | 0.72 | MAOA (0.40) | MEN1KMT2ADAORAB9AHTT | |
| SCHEMBL20780451 | 0.71 | CYP2A6 (0.50) | MEN1KMT2ADAORAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2017207776-A1 | SYSTEM FOR DISPENSING A COSMETIC PRODUCT | L'OREAL (FR) | 2017-12-07 | — | — | WO | disclosed |