Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497347 | 0.80 | ACHE (0.58) | CA2ALDH1A1APPCYP3A4SMN1; SMN2 | |
| SCHEMBL11880333 | 0.77 | TTR (0.50) | CA2ALDH1A1APPCYP3A4CYP1A2 | |
| SCHEMBL22601651 | 0.76 | ALDH1A1 (0.82) | CA2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL2742606 | 0.75 | KDM4E (0.66) | CYP3A4LMNACYP1A2CYP2D6BLM | |
| SCHEMBL19682008 | 0.75 | CA2 (0.53) | CA2ALDH1A1APPGAATUBB4A | |
| SCHEMBL27704501 | 0.74 | AKR1B1 (0.53) | CA2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL3617665 | 0.73 | ALDH1A1 (0.67) | ALDH1A1APPGAACYP3A4LMNA | |
| SCHEMBL21933490 | 0.72 | TUBB4A (0.68) | CA2GAATUBB4ATUBBTUBA3C | |
| SCHEMBL17955400 | 0.72 | PTGS2 (0.42) | CA2ALDH1A1GAATUBB1CYP3A4 | |
| SCHEMBL17653880 | 0.72 | GAA (0.64) | CA2ALDH1A1APPGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2017207776-A1 | SYSTEM FOR DISPENSING A COSMETIC PRODUCT | L'OREAL (FR) | 2017-12-07 | — | — | WO | disclosed |