SCHEMBL19684029

SCHEMBL19684029

O=C(O)C12CC3CC(CC(OC(O)c4cc(I)cc(I)c4I)(C3)C1)C2

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.34
▸ GAA P10253 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19678506 0.77 KMT2A (0.35) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL19985161 0.69 KMT2A (0.39) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL21794428 0.67 KMT2A (0.37) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL14670207 0.64 PKM (0.44) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL7748923 0.64 ALDH1A1 (0.47) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL5192002 0.63 PKM (0.43) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL5608294 0.62 ALDH1A1 (0.50) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL164232 0.62 L3MBTL1 (0.58) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL13589980 0.62 L3MBTL1 (0.58) KMT2AGAAPKML3MBTL1ALDH1A1
SCHEMBL14493665 0.62 L3MBTL1 (0.58) KMT2AGAAPKML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10295904-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-05-21 — — US disclosed
US-20170351177-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170351177-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, EWSR1, INSRR KMT2A 1725/4885GAA 3804/4885PKM 3118/4885
US-10295904-B2 Resist composition and patterning process INSR, EWSR1, INSRR KMT2A 1725/4885GAA 3804/4885PKM 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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