Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4490398 | 0.98 | PLOD2 (0.62) | PLOD2ALDH1A1APPGAAHCAR3 | |
| Bromide SCHEMBL497460 | 0.98 | PLOD2 (0.62) | PLOD2ALDH1A1APPGAAHCAR3 | |
| Bromide SCHEMBL3204603 | 0.96 | PLOD2 (0.61) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL7075878 | 0.83 | PLOD2 (0.69) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL10320930 | 0.83 | PLOD2 (0.89) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL29554726 | 0.83 | PLOD2 (0.89) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL27754304 | 0.82 | HDAC1 (0.63) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL6440012 | 0.82 | PLOD2 (0.67) | PLOD2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL13002415 | 0.81 | KMO (0.67) | PLOD2ALDH1A1PTPN1GSK3BMEN1 | |
| SCHEMBL905439 | 0.80 | PLOD2 (0.65) | PLOD2ALDH1A1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235863-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-21 | — | — | US | claimed |
| WO-2012164572-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-12-06 | — | — | WO | claimed |
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| EP-4676475-A1 | HIV-1P ROTEASE INHIBITORS AND USES THEREOF | Purdue Research Foundation (US) | 2026-01-14 | — | — | EP | disclosed |
| US-12503477-B2 | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | GENZYME CORPORATION | 2025-12-23 | — | — | US | disclosed |
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | PRISM MEDICINES, INC. | 2025-01-09 | — | — | US | disclosed |
| WO-2024206093-A1 | HIV-1P ROTEASE INHIBITORS AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2024-10-03 | — | — | WO | disclosed |
| CN-115850258-B | Synthesis method of masitinib | 东北林业大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-115850258-B | Synthesis method of masitinib | 东北林业大学 | 2024-09-24 | — | — | CN | disclosed |
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-5457111-A | Side effect reduction | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | disclosed |
| WO-1995021817-A1 | SUBSTITUTED SPIRO COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0641797-A1 | Cephem derivatives and antimicrobial agents containing the same | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5393790-A | Diphenyl- or phenyl/pyridyl-substituted spiroheptenes, -octenes,-nonenes or -decenes; cyclooxygenase II inhibitors; side effect reduction; antipyretics; antiarthritic agents | G.D. SEARLE & CO. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |
| EP-0571471-A1 | 5-HETEROYL INDOLE DERIVATIVES. | PFIZER (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992013856-A1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |
| US-4171444-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN ALIPHATIC ALDEHYDE, DEHYDRATING-DEHYDROGENATION CATALYSTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | PLOD2 1446/4885ALDH1A1 289/4885APP 2018/4885 |
| US-20140235863-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | TST, NQO1, FNTB | PLOD2 2606/4885ALDH1A1 111/4885APP 1249/4885 |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | AHR, ARNT, HCAR1 | PLOD2 1446/4885ALDH1A1 289/4885APP 2018/4885 |
| US-12029739-B2 | SHP2 inhibitor and use thereof | PTPN1, PTPN5, PTPN2 | PLOD2 3620/4885ALDH1A1 3565/4885APP 1363/4885 |
| US-12503477-B2 | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | CSF1R, CSF3R, IL1RN | PLOD2 4202/4885ALDH1A1 1517/4885APP 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.