SCHEMBL19685445

SCHEMBL19685445

CC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCCN

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 10/20 0.51
CAPN1 P07384 3/20 0.45
KMT2A Q03164 1/20 0.45
ITGB3 P05106 2/20 0.45
ITGA2B P08514 2/20 0.45
CTSB P07858 1/20 0.44
APLNR P35414 1/20 0.44
ACE2 Q9BYF1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21351085 0.89 STAT3 (0.51) STAT3CAPN1KMT2ACTSBACE2
SCHEMBL21705369 0.88 STAT3 (0.50) STAT3CAPN1KMT2ACTSBACE2
SCHEMBL19679843 0.84 APLNR (0.49) STAT3APLNRACE2
SCHEMBL21348091 0.83 ACE2 (0.48) STAT3CAPN1KMT2ACTSBACE2
SCHEMBL7386429 0.82 ACE (0.55) KMT2AACE2
SCHEMBL19685446 0.81 ACE (0.56) ACE2
SCHEMBL19685305 0.80 P2RX7 (0.48) KMT2A
SCHEMBL28346593 0.80 XIAP (0.50) STAT3CAPN1KMT2ACTSBACE2
SCHEMBL22300346 0.77 OPRM1 (0.51) CAPN1KMT2ACTSBAPLNR
SCHEMBL15214200 0.77 OPRM1 (0.52) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11707507-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog, and a co-polyamino acid ADOCIA (FR) 2023-07-25 US disclosed
US-20200306346-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID ADOCIA (FR) 2020-10-01 US disclosed
US-20200046805-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AND A CO-POLYAMINO ACID ADOCIA (FR) 2020-02-13 US disclosed
US-10463717-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog, and a co-polyamino acid ADOCIA (FR) 2019-11-05 US disclosed
US-20190275108-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID ADOCIA (FR) 2019-09-12 US disclosed
US-20190275110-A1 COMPOSITIONS IN THE FORM OF AN INJECTALE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID ADOCIA (FR) 2019-09-12 US disclosed
US-20190274953-A1 PH 7 INJECTABLE SOLUTION COMPRISING AT LEAST ONE BASIC INSULIN WITH A PI COMPRISED FROM 5.8 TO 8.5 AND A CO-POLYAMINOACIDE BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2019-09-12 US disclosed
US-10383918-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a statistical co-polyamino acid ADOCIA (FR) 2019-08-20 US disclosed
US-20180193421-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AND A CO-POLYAMINO ACID ADOCIA (FR) 2018-07-12 US disclosed
US-20170348394-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A STATISTICAL CO-POLYAMINO ACID ADOCIA (FR) 2017-12-07 US disclosed
US-20170348395-A1 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid ADOCIA (FR) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190275108-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID IAPP, GPR119, GLP1R STAT3 468/4885CAPN1 2370/4885KMT2A 4616/4885
US-20180193421-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AND A CO-POLYAMINO ACID IAPP, GPR119, GIPR STAT3 472/4885CAPN1 2587/4885KMT2A 4535/4885
US-10463717-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog, and a co-polyamino acid IAPP, GPR119, GIPR STAT3 463/4885CAPN1 2664/4885KMT2A 4591/4885
US-20200306346-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID GCG, GLP1R, GCGR STAT3 101/4885CAPN1 3875/4885KMT2A 2543/4885
US-20200046805-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AND A CO-POLYAMINO ACID IAPP, INSR, GLP1R STAT3 208/4885CAPN1 2328/4885KMT2A 4720/4885
US-20170348394-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A STATISTICAL CO-POLYAMINO ACID GCG, GLP1R, IAPP STAT3 102/4885CAPN1 3974/4885KMT2A 2983/4885
US-10383918-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a statistical co-polyamino acid GCG, GLP1R, IAPP STAT3 102/4885CAPN1 3974/4885KMT2A 2983/4885
US-20190275110-A1 COMPOSITIONS IN THE FORM OF AN INJECTALE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID GCG, GLP1R, IAPP STAT3 100/4885CAPN1 3190/4885KMT2A 3000/4885
US-20170348395-A1 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid GCG, GLP1R, IAPP STAT3 98/4885CAPN1 3877/4885KMT2A 2724/4885
US-11707507-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog, and a co-polyamino acid IAPP, INSR, GLP1R STAT3 208/4885CAPN1 2328/4885KMT2A 4720/4885
US-20190274953-A1 PH 7 INJECTABLE SOLUTION COMPRISING AT LEAST ONE BASIC INSULIN WITH A PI COMPRISED FROM 5.8 TO 8.5 AND A CO-POLYAMINOACIDE BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS GPR119, INSR, GCG STAT3 172/4885CAPN1 1753/4885KMT2A 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.