SCHEMBL19685741

SCHEMBL19685741

O=C1OCc2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRF1 P14222 15/20 0.55
MAPT P10636 2/20 0.49
LMNA P02545 2/20 0.49
GAA P10253 1/20 0.49
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
ACHE P22303 1/20 0.45
RECQL P46063 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686095 0.89 MAPT (0.53) PRF1MAPTLMNAGAAMAOA
SCHEMBL19685756 0.88 MAOA (0.47) PRF1MAPTLMNAGAAMAOA
SCHEMBL19686075 0.85 PARP10 (0.44) PRF1MAPTLMNAMAOAMAOB
SCHEMBL19685757 0.82 MAOA (0.42) PRF1MAPTLMNAMAOAMAOB
SCHEMBL19685754 0.80 MAOA (0.52) MAPTLMNAGAAMAOAMAOB
SCHEMBL16573996 0.78 PRF1 (0.61) PRF1MAPTLMNAGAAMAOA
SCHEMBL10110906 0.77 TDP2 (0.47) MAPTLMNAALDH1A1
SCHEMBL19685808 0.77 TYRO3 (0.40) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL19685911 0.75 HSD17B1 (0.61) MAPTMAOAMAOBALDH1A1
SCHEMBL19966686 0.74 PRF1 (0.61) PRF1MAPTLMNAGAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS PRF1 840/4885MAPT 4713/4885LMNA 3026/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS PRF1 840/4885MAPT 4713/4885LMNA 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.