SCHEMBL19685811

SCHEMBL19685811

O=C1OCCc2ccc(-n3c4ccc(-c5ccccc5)cc4c4cc(-c5ccccc5)ccc43)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37
TYRO3 Q06418 1/20 0.36
NTRK2 Q16620 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
PDGFRB P09619 1/20 0.35
SRC P12931 1/20 0.35
KDR P35968 1/20 0.35
TDP2 O95551 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
PRKDC P78527 4/20 0.34
MMP9 P14780 1/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
MAOB P27338 1/20 0.32
FAAH O00519 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686259 0.90 LMNA (0.40) EDNRBEDNRATYRO3NTRK2CLK4
SCHEMBL19685759 0.87 MAOB (0.43) EDNRBEDNRATYRO3NTRK2CLK4
SCHEMBL19685810 0.86 L3MBTL1 (0.38) EDNRBEDNRAMMP9ALDH1A1KDM4E
SCHEMBL19685701 0.82 LMNA (0.43) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL19686167 0.82 APP (0.33) EDNRBEDNRAMMP9ALDH1A1LMNA
SCHEMBL19685744 0.80 LMNA (0.55) ALDH1A1LMNAMAOBMAPT
SCHEMBL25565473 0.78 KDM4E (0.41) EDNRBEDNRATYRO3NTRK2CLK4
SCHEMBL15613804 0.77 PARP10 (0.40) EDNRBEDNRATDP2PARP10PARP11
SCHEMBL19685998 0.77 SDCBP (0.40) TYRO3NTRK2CLK4DYRK1BTDP2
SCHEMBL19686154 0.77 NPC1 (0.50) TYRO3NTRK2CLK4DYRK1BTDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS EDNRB 2952/4885EDNRA 2001/4885TYRO3 1980/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS EDNRB 2952/4885EDNRA 2001/4885TYRO3 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.