Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687591 | 0.81 | MEN1 (0.43) | RAB9AKDM4ESCARB1 | |
| SCHEMBL19687594 | 0.78 | ESR1 (0.40) | POLBRAB9ALMNA | |
| SCHEMBL19687577 | 0.78 | MEN1 (0.46) | POLBRAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL19687581 | 0.77 | KDM4E (0.44) | POLBRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL19687586 | 0.76 | MEN1 (0.46) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL19687598 | 0.76 | RAB9A (0.35) | RAB9AKDM4ELMNAHTT | |
| SCHEMBL19687576 | 0.76 | RAB9A (0.35) | RAB9ALMNACYP1A2 | |
| SCHEMBL19687583 | 0.74 | MEN1 (0.43) | POLBRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL19687584 | 0.74 | PARG (0.39) | RAB9APARG | |
| SCHEMBL19687579 | 0.72 | RAB9A (0.33) | RAB9AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |