Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | DDX3X | O00571 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965022 | 0.88 | BCAT2 (0.44) | BCAT2PTGESALOX5CSNK1A1TYRO3 | |
| SCHEMBL18584726 | 0.84 | BCAT2 (0.61) | BCAT2PTGESALOX5CSNK1A1TYRO3 | |
| SCHEMBL1968589 | 0.83 | ALDH1A1 (0.40) | BCAT2CSNK1A1TYRO3DYRK1BPARP1 | |
| SCHEMBL1966405 | 0.73 | BCAT2 (0.40) | BCAT2PTGESALOX5CSNK1A1TYRO3 | |
| SCHEMBL11611572 | 0.72 | NPC1 (0.56) | NPC1RAB9ADDX3XMEN1KMT2A | |
| SCHEMBL27947437 | 0.71 | BCAT2 (0.43) | BCAT2CSNK1A1TYRO3DYRK1BPARP1 | |
| SCHEMBL1968945 | 0.68 | CSNK2A2 (0.71) | NPC1RAB9ADDX3XMEN1KMT2A | |
| SCHEMBL25353879 | 0.67 | HNF4A (0.49) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5878337 | 0.67 | BCAT2 (0.87) | BCAT2CSNK1A1TYRO3DYRK1BPARP1 | |
| SCHEMBL28054906 | 0.67 | BCAT2 (0.56) | BCAT2CSNK1A1TYRO3DYRK1BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |