SCHEMBL19690646

SCHEMBL19690646

CCc1ccc2c(c1CC)C(c1cccc(C)c1)=C(c1ccccc1)C2(C(=O)O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 3/20 0.36
▸ CNR1 P21554 1/20 0.36
▸ KMO O15229 1/20 0.33
▸ GRIA2 P42262 1/20 0.33
▸ GRIA4 P48058 1/20 0.33
▸ CTSA P10619 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ TP53 P04637 2/20 0.32
▸ POLB P06746 2/20 0.32
▸ PPARG P37231 1/20 0.32
▸ PPARA Q07869 1/20 0.32
▸ BACE1 P56817 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ CTDSP1 Q9GZU7 1/20 0.32
▸ GAA P10253 1/20 0.31
▸ PTGES O14684 1/20 0.31
▸ ALOX5 P09917 1/20 0.31
▸ FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18663361 0.89 ADORA3 (0.33) L3MBTL1NPC1RAB9AMAPTGAA
SCHEMBL19690686 0.84 GSK3B (0.40) MAPTSMN1; SMN2
SCHEMBL19690388 0.78 ADORA3 (0.32) NPC1RAB9AMAPTGAASMN1; SMN2
SCHEMBL19690414 0.72 PDK2 (0.34) ADORA3
SCHEMBL19690581 0.70 MTNR1A (0.36) GRIA2GRIA4NPC1RAB9AMAPT
SCHEMBL19690582 0.70 CCNC (0.34) MAPT
SCHEMBL18663372 0.69 MAPT (0.39) RAB9AMAPT
SCHEMBL18663328 0.66 SMN1; SMN2 (0.40) L3MBTL1TP53BACE1NPC1RAB9A
SCHEMBL18663310 0.64 TDP1 (0.36) CNR1POLBNPC1RAB9AMAPT
SCHEMBL18663370 0.64 ADORA3 (0.33) NPC1RAB9AMAPTGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 — — US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B CNR2 405/4885CNR1 976/4885KMO 2868/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 CNR2 1409/4885CNR1 2765/4885KMO 1743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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