Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.85 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 3/20 | 0.80 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.80 |
| ▸ | AURKA | O14965 | 2/20 | 0.80 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.80 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18918369 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29396999 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28216089 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28041178 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19693052 | 0.99 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15299842 | 0.99 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29530678 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.96 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | claimed |
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | AGAIN BIO APS (DK) | 2026-01-29 | — | — | US | claimed |
| US-12503711-B2 | Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism | GENOMATICA, INC. (US) | 2025-12-23 | — | — | US | claimed |
| CN-114728871-B | Microorganisms and methods for reducing byproducts | 基因组股份公司 | 2024-12-27 | — | — | CN | claimed |
| US-20230332194-A1 | MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING ADIPATE, 6-AMINOCAPROATE, HEXAMETHYLENEDIAMINE OR CAPROLACTAM RELATED THERETO | GENOMATICA INC (US) | 2023-10-19 | — | — | US | claimed |
| US-11753663-B2 | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing adipate, 6-aminocaproate, hexamethylenediamine or caprolactam related thereto | GENOMATICA, INC. (US) | 2023-09-12 | — | — | US | claimed |
| US-11702682-B2 | Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism | GENOMATICA, INC. (US) | 2023-07-18 | — | — | US | claimed |
| EP-3611254-B1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF HEXAMETHYLENEDIAMINE | GENOMATICA INC (US) | 2023-07-05 | — | — | EP | claimed |
| US-20220403420-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | AGAIN BIO APS (DK) | 2022-12-22 | — | — | US | claimed |
| US-11447804-B2 | Producing adipate, 6-aminocaproate, hexamethylenediamine or caprolactam in the presence of methanol using a microorganism having increased availability of reducing equivalents | GENOMATICA, INC. (US) | 2022-09-20 | — | — | US | claimed |
| WO-2014099725-A1 | MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING ADIPATE, 6-AMINOCAPROATE, HEXAMETHYLENEDIAMINE OR CAPROLACTAM RELATED THERETO | GENOMATICA, INC. (US) | 2014-06-26 | — | — | WO | claimed |
| WO-2014028026-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2014-02-20 | — | — | WO | claimed |
| US-20130303723-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2013-11-14 | — | — | US | claimed |
| US-8404465-B2 | Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks | CELEXION, LLC (US) | 2013-03-26 | — | — | US | claimed |
| US-20130017593-A1 | Biological Synthesis of Difunctional Hexanes and Pentanes from Carbohydrate Feedstocks | CELEXION, LLC (US) | 2013-01-17 | — | — | US | claimed |
| WO-2012177721-A1 | MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2012-12-27 | — | — | WO | claimed |
| US-20120301950-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL HEXANES AND PENTANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC | 2012-11-29 | — | — | US | claimed |
| EP-2427544-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | Genomatica, Inc. (US) | 2012-03-14 | — | — | EP | claimed |
| US-20100317069-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | AGAIN BIO APS (DK) | 2010-12-16 | — | — | US | claimed |
| WO-2010129936-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2010-11-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028651-A1 | METHOD OF PRODUCING & PROCESSING DIAMINES | DDC, DAO, ODC1 | NAA50 69/4885CHAT 77/4885EP300 1948/4885 |
| US-12577591-B2 | Microorganisms and methods for increasing co-factors | ABAT, HADHB, MMAB | NAA50 278/4885CHAT 1499/4885EP300 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.