Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.85 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 3/20 | 0.80 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.80 |
| ▸ | AURKA | O14965 | 2/20 | 0.80 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.80 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284786 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL18918369 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28216089 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28041178 | 1.00 | NAA50 (0.85) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL19693052 | 0.99 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL15299842 | 0.99 | NAA50 (0.86) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL29530678 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL22556110 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59962 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.96 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577594-B2 | Engineered microorganisms and methods for improved aldehyde dehydrogenase activity | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | claimed |
| EP-4642908-A2 | LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE | Genomatica, Inc. (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2024145507-A2 | LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE | GENOMATICA, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| EP-4051657-A1 | MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS | Genomatica, Inc. (US) | 2022-09-07 | — | — | EP | claimed |
| EP-4048781-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | Genomatica, Inc. (US) | 2022-08-31 | — | — | EP | claimed |
| US-20220235385-A1 | ENGINEERED MICROORGANISMS AND METHODS FOR IMPROVED ALDEHYDE DEHYDROGENASE ACTIVITY | AGAIN BIO APS (DK) | 2022-07-28 | — | — | US | claimed |
| EP-3959310-A1 | ENGINEERED TRANSAMINASE AND METHODS OF MAKING AND USING | Genomatica, Inc. (US) | 2022-03-02 | — | — | EP | claimed |
| EP-3959327-A1 | ENGINEERED TRANS-ENOYL COA REDUCTASE AND METHODS OF MAKING AND USING | Genomatica, Inc. (US) | 2022-03-02 | — | — | EP | claimed |
| US-12577594-B2 | Engineered microorganisms and methods for improved aldehyde dehydrogenase activity | GENOMATICA, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | GENOMATICA, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4662192-A1 | MICROORGANISMS AND METHODS FOR REDUCING BY-PRODUCTS | Genomatica, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4642908-A2 | LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE | Genomatica, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20250305013-A1 | Methods and Compositions for Making Amide Compounds | GENOMATICA, INC. (US) | 2025-10-02 | — | — | US | disclosed |
| US-20240294950-A1 | MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS | AGAIN BIO APS (DK) | 2024-09-05 | — | — | US | disclosed |
| EP-4048781-A1 | MICROORGANISMS AND METHODS FOR INCREASING CO-FACTORS | Genomatica, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| US-20220235385-A1 | ENGINEERED MICROORGANISMS AND METHODS FOR IMPROVED ALDEHYDE DEHYDROGENASE ACTIVITY | AGAIN BIO APS (DK) | 2022-07-28 | — | — | US | disclosed |
| WO-2022155554-A1 | METHODS AND COMPOSITIONS FOR MAKING AMIDE COMPOUNDS | GENOMATICA, INC. (US) | 2022-07-21 | — | — | WO | disclosed |
| CN-114341344-A | Engineered microorganisms and methods for improving aldehyde dehydrogenase activity | 基因组股份公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3959310-A1 | ENGINEERED TRANSAMINASE AND METHODS OF MAKING AND USING | Genomatica, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| EP-3959327-A1 | ENGINEERED TRANS-ENOYL COA REDUCTASE AND METHODS OF MAKING AND USING | Genomatica, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529078-B2 | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | ALDOA, FDPS, DERA | NAA50 298/4885CHAT 1363/4885EP300 1390/4885 |
| US-12577594-B2 | Engineered microorganisms and methods for improved aldehyde dehydrogenase activity | ACADM, ALDH7A1, ADSL | NAA50 211/4885CHAT 350/4885EP300 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.