Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690460 | 0.78 | KCNQ2 (0.39) | KIF11ALDH1A1PKMMAPTKDM4E | |
| SCHEMBL19695407 | 0.76 | DPP7 (0.39) | KIF11ALDH1A1MAPTKDM4ECYP2C19 | |
| SCHEMBL28471479 | 0.71 | ALDH1A1 (0.53) | KIF11ALDH1A1PKMMAPTKDM4E | |
| SCHEMBL29188533 | 0.71 | KIF11 (0.51) | KIF11ALDH1A1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL28469639 | 0.68 | KIF11 (0.51) | KIF11ALDH1A1PKMMAPTKDM4E | |
| SCHEMBL3712182 | 0.67 | MRGPRX4 (0.53) | KIF11MAPT | |
| SCHEMBL1450826 | 0.65 | KIF11 (0.47) | KIF11ALDH1A1MAPTKDM4ECYP2C19 | |
| SCHEMBL17797013 | 0.64 | KIF11 (0.48) | KIF11ALDH1A1KDM4ECYP2C19HPGD | |
| SCHEMBL17797016 | 0.64 | KIF11 (0.51) | KIF11BACE1 | |
| SCHEMBL23581754 | 0.64 | KDM4E (0.53) | KIF11ALDH1A1KDM4ECYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468947-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SciFluor Life Sciences, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |